Cruz Manuelos, a rough-around-the-edges but passionate young Marine, is recruited to join the CIA's Lioness Engagement Team to help bring down a terrorist organization from within. Joe, the station chief of the Lioness program, is tasked with training, managing and leading her female undercover operatives.
Joe attempts to balance her personal and professional life as the tip of the CIA's spear in the war on terror; the Lioness Program enlists Cruz to operate undercover alongside Joe among the power brokers of State terrorism.
In Season 2, as the CIA's fight against terror moves closer to home, Joe, Kaitlyn, and Byron enlist a new Lioness operative to infiltrate a previously unknown threat. With pressure mounting from all sides, Joe is forced to confront the profound personal sacrifices she has made as the leader of the Lioness program.
In Season Three, hidden networks, foreign operatives, and personal betrayals collide. Joe walks the line between duty and home as unseen forces circle her world. Patterns appear where they shouldn't, names vanish, and paths rearrange. Guided by Kaitlyn and Westfield, Joe confronts enemies operating in the shadows, leaving her to reckon with a war that now reaches into every part of her life.